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  1. Home
  2. Chung Shan Medical University
  3. Project/研究計畫(老師)
  4. 甲型硫辛酸對慢性睡眠剝奪引發的胃腸功能障礙之保護與治療作用:黏膜穩態及分子機制之研究
 
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甲型硫辛酸對慢性睡眠剝奪引發的胃腸功能障礙之保護與治療作用:黏膜穩態及分子機制之研究

  • Details
Project title
114學年度國家科學及技術委員會補助研究計畫
Acronym
專題研究計畫
Internal ID
NSTC114-2320-B040-023-MY2
Principal Investigator
Chen, Li-you  
Status
research project
Start Date
August 1, 2025
End Date
July 31, 2026
Organizations
School of Medicine  
Partner Organizations
National Science and Technology Council  
Project Web Site
https://www.grb.gov.tw/search/planDetail?id=17956225
Keywords
甲型硫辛酸
慢性睡眠剝奪
氧化壓力
胃腸功能障礙
細胞化生
Description
慢性睡眠剝奪已然成為現今社會最常見的問題,長期睡眠剝奪會導致氧化壓力與發炎反應大增,並造成胃腸黏膜細胞損傷。本計畫擬使用動物實驗詳實探討慢性睡眠剝奪所衍生之胃腸功能障礙機制之外,並且進一步探究甲型硫辛酸的介入對胃腸黏膜細胞之潛在保護影響。計畫所得之成果除了宣導充足睡眠的重要性之外,並對臨床上使用甲型硫辛酸預防、改善或治療胃腸功能障礙有顯著的參考價值與貢獻。
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