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  4. 探討GLP-1訊息參與糖脂毒性導致周邊神經病變之分子機制
 
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探討GLP-1訊息參與糖脂毒性導致周邊神經病變之分子機制

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Project title
109學年度教學研究計畫
Acronym
教學研究計畫
Principal Investigator
王威傑  
Start Date
August 1, 2020
Organizations
College of Medicine  
School of Medicine  
Partner Organizations
National Science and Technology Council  
Keywords
糖尿病神經病變
Liraglutide
糖脂毒性
AMPK / Sirt1訊息路徑
神經保護。
Description
計畫名稱:探討GLP-1訊息參與糖脂毒性導致周邊神經病變之分子機制
成果報告:
執行起迄:2020/08/01~2021/07/31
總核定金額:1,050,000元 (各年度經費明細)
計畫概述:糖尿病周邊神經病變是患者最常見的併發症,也是造成殘障的主要原因,目前詳細的病理機轉仍不清楚,但一般認為跟長期的糖脂毒性有關。GLP-1促效劑是一種新型的抗糖尿病用藥,近年發現其除了可調控血糖外...(詳)
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