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  4. 探討ATP1B3調節miR-331-5p/CDK1路徑於骨肉瘤的進展和轉移之機制
 
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探討ATP1B3調節miR-331-5p/CDK1路徑於骨肉瘤的進展和轉移之機制

  • Details
Project title
114學年度國家科學及技術委員會補助研究計畫
Acronym
專題研究計畫
Internal ID
NSTC114-2314-B040-019
Principal Investigator
Lu, Ko-Hsiu  
Status
research project
Start Date
August 1, 2025
End Date
July 31, 2026
Organizations
School of Medicine  
Partner Organizations
National Science and Technology Council  
Project Web Site
https://www.grb.gov.tw/search/planDetail?id=17972365
Keywords
骨肉瘤
癌症轉移
ATP1B3
CDK1
miR-331-5p
Description
骨癌的患者其預後差且存活率低,主要原因是骨癌具有高度轉移的特性。本計畫擬探討 ATP1B3在骨癌轉移過程的表現及其調控CDK1之機制。了解此機制,可以利用ATP1B3或CDK1抑制劑來輔助治療並降低骨癌的轉移能力,可提高骨癌患者的存活率。
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