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  1. Home
  2. Chung Shan Medical University
  3. Project/研究計畫(老師)
  4. 以阻斷Linc-ROR分子標靶來探討山竹黃酮素抑制頰黏膜纖維母細胞轉分化為肌纖維母細胞之調控機轉探討及臨床前應用評估
 
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以阻斷Linc-ROR分子標靶來探討山竹黃酮素抑制頰黏膜纖維母細胞轉分化為肌纖維母細胞之調控機轉探討及臨床前應用評估

  • Details
Project title
109學年度教學研究計畫
Acronym
教學研究計畫
Principal Investigator
李育賢  
Start Date
August 1, 2020
Organizations
College of Oral Medicine  
School of Dentistry  
Partner Organizations
National Science and Technology Council  
Keywords
口腔黏膜下纖維化症
Linc-ROR
α-山竹黃酮素
Description
計畫名稱:以阻斷Linc-ROR分子標靶來探討山竹黃酮素抑制頰黏膜纖維母細胞轉分化為肌纖維母細胞之調控機轉探討及臨床前應用評估
成果報告:
執行起迄:2020/08/01~2023/07/31
總核定金額:3,546,000元 (各年度經費明細)
計畫概述:嚼食檳榔是造成口腔黏膜下纖維化症最主要的因子,目前口腔癌黏膜下纖維化症尚缺專一性治療法,本研究可藉山竹黃酮及Linc-ROR來開發口腔黏膜纖維化症新穎療法及生物標記,可用來減少病患社交、經濟與...(詳)
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