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Chung Shan Medical University
Project/研究計畫(老師)
研究原薯蕷皂苷誘發肝癌細胞內氧化壓力促進粒線體凋亡路徑及作為輔助分子標靶藥物之分子機制
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研究原薯蕷皂苷誘發肝癌細胞內氧化壓力促進粒線體凋亡路徑及作為輔助分子標靶藥物之分子機制
Details
Primary Data
Project title
110學年度教學研究計畫
Acronym
教學研究計畫
Principal Investigator
邱慧玲
Start Date
August 1, 2021
Organizations
College of Medical Science and Technology
Department of Medical Laboratory and Biotechnology
Partner Organizations
National Science and Technology Council
Description
Keywords
肝細胞癌
原薯蕷皂苷
細胞凋亡
內質網壓力
粒線體動態平衡
Description
計畫名稱:研究原薯蕷皂苷誘發肝癌細胞內氧化壓力促進粒線體凋亡路徑及作為輔助分子標靶藥物之分子機制
成果報告:
執行起迄:2021/08/01~2022/07/31
總核定金額:1,000,000元 (各年度經費明細)
計畫概述:本計畫將瞭解PTD誘發ROS促進粒線體凋亡作用的分子機轉,及提供Mfn1/Bak/IP3R為分子標的及應用於肝癌治療上具有作為抗癌作用以及輔助標靶sorafenib藥物發展的潛力,為學術領域重...(詳)
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