探討安卓錠C經抑制穀醯胺酸分解作用於防治口腔黏膜下纖維化之分子機轉及臨床前應用 (延續性計畫)

The medicinal fungus Taiwanofungus camphoratus, recognized for its wide range of health benefits, is widely used in the development of health supplement products, demonstrating significant medical and economic value. This study aims to evaluate the therapeutic efficacy of Antrodin C, an active compound derived from T. camphoratus, on oral submucous fibrosis (OSF) and further elucidate its anti-fibrotic effects by investigating its modulation of OSF metabolic pathways via lncRNA SNHG7-mediated epigenetic regulation. Academically, this research will pioneer the investigation of metabolic dysregulation in OSF, deepen our understanding of lncRNA-mediated regulation of metabolic pathways, and offer a novel perspective on the potential of T. camphoratus' active components in ameliorating diseases through lncRNA epigenetic modulation. From a social and medical perspective, this study is expected to yield new therapeutic and diagnostic strategies for OSF patients, improving their health and advancing precision medicine. Economically, it will enhance the application potential of T. camphoratus in the pharmaceutical field, strengthen its economic benefits, and promote the transformation and upgrading of Taiwan's local industry.