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  1. Home
  2. Chung Shan Medical University
  3. Project/研究計畫(老師)
  4. 鎳在台灣不抽菸肺癌之角色
 
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鎳在台灣不抽菸肺癌之角色

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Project title
101學年度國家科學及技術委員會補助研究計畫
Acronym
專題研究計畫
Principal Investigator
吳子卿
Start Date
August 1, 2012
End Date
July 31, 2015
Organizations
School of Dentistry  
Partner Organizations
National Science and Technology Council  
Keywords
肺癌
鎳
IL-10
上皮-間質型態轉換
纖維化
Nrf2
巨噬細胞
檞皮酮
白楊素
Description
關於鎳暴露誘發肺癌發展的機制目前所知不多。因此本計畫將探討:(1)鎳累積在肺組織中,是否會增加肺癌細胞EGFR的突變,鎳是否會藉由誘發miR-21的表現而抑制RECK及SPRY2蛋白的表現增加...(詳)
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