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Chung Shan Medical University
Project/研究計畫(老師)
鑑定抗肺癌胜肽LT1-3-PEG的標靶蛋白和訊息傳遞路徑
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鑑定抗肺癌胜肽LT1-3-PEG的標靶蛋白和訊息傳遞路徑
Details
Primary Data
Project title
110學年度教學研究計畫
Acronym
教學研究計畫
Principal Investigator
蔡菁華
Start Date
August 1, 2021
Organizations
College of Medicine
Institute of Medicine
Partner Organizations
National Science and Technology Council
Description
Keywords
LT1-3
胜肽
p53
JNK
肺癌
順鉑
Description
計畫名稱:鑑定抗肺癌胜肽LT1-3-PEG的標靶蛋白和訊息傳遞路徑
成果報告:
執行起迄:2021/08/01~2022/07/31
總核定金額:1,165,000元 (各年度經費明細)
計畫概述:我們由抑癌基因Slit2中鑑定出一個8個胺基酸的胜肽藥物,此胜肽具有抑制肺癌細胞生長、侵犯的能力之外,並可以促進第一線化療藥物順鉑的療效,但不影響正常細胞的生長。在動物實驗上,此胜肽藥物可以抑...(詳)
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