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  4. 鑑定抗肺癌胜肽LT1-3-PEG的標靶蛋白和訊息傳遞路徑
 
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鑑定抗肺癌胜肽LT1-3-PEG的標靶蛋白和訊息傳遞路徑

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Project title
110學年度教學研究計畫
Acronym
教學研究計畫
Principal Investigator
蔡菁華  
Start Date
August 1, 2021
Organizations
College of Medicine  
Institute of Medicine  
Partner Organizations
National Science and Technology Council  
Keywords
LT1-3
胜肽
p53
JNK
肺癌
順鉑
Description
計畫名稱:鑑定抗肺癌胜肽LT1-3-PEG的標靶蛋白和訊息傳遞路徑
成果報告:
執行起迄:2021/08/01~2022/07/31
總核定金額:1,165,000元 (各年度經費明細)
計畫概述:我們由抑癌基因Slit2中鑑定出一個8個胺基酸的胜肽藥物,此胜肽具有抑制肺癌細胞生長、侵犯的能力之外,並可以促進第一線化療藥物順鉑的療效,但不影響正常細胞的生長。在動物實驗上,此胜肽藥物可以抑...(詳)
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