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Chung Shan Medical University
Project/研究計畫(老師)
口腔黏膜下纖維化症之分子機制剖析及標靶策略研發:聚焦於檳榔素引起HOXD-AS1-miR-143-CTGF致病軸活化
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口腔黏膜下纖維化症之分子機制剖析及標靶策略研發:聚焦於檳榔素引起HOXD-AS1-miR-143-CTGF致病軸活化
Details
Primary Data
Project title
110學年度教學研究計畫
Acronym
教學研究計畫
Principal Investigator
彭芷瑜
Start Date
August 1, 2021
Organizations
College of Oral Medicine
School of Dentistry
Partner Organizations
National Science and Technology Council
Description
Keywords
口腔黏膜下纖維化
長鏈非編碼核醣核酸
HOXD-AS1
微型核醣核酸-143
結締組織生長因子
競爭性內源RNA
Description
計畫名稱:口腔黏膜下纖維化症之分子機制剖析及標靶策略研發:聚焦於檳榔素引起HOXD-AS1-miR-143-CTGF致病軸活化
成果報告:
執行起迄:2021/08/01~2022/07/31
總核定金額:1,100,000元 (各年度經費明細)
計畫概述:完成此計畫將釐清檳榔鹼誘發HOXD-AS1/miR-143/CTGF調控軸於口腔黏膜下纖化致病機制並運用CRISPR/Cas9基因編輯技術刪除HOXD-AS1以開發抗口腔黏膜下纖維化治療診斷策...(詳)
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