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  1. Home
  2. Chung Shan Medical University
  3. Project/研究計畫(老師)
  4. 以近紅外光與機械力協同刺激牙周韌帶分泌細胞激素影響骨重塑/骨免疫機制( II )
 
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以近紅外光與機械力協同刺激牙周韌帶分泌細胞激素影響骨重塑/骨免疫機制( II )

  • Details
Project title
114學年度國家科學及技術委員會補助研究計畫
Acronym
專題研究計畫
Internal ID
NSTC114-2314-B040-002
Principal Investigator
Kao, Chia-Tze  
Status
research project
Start Date
August 1, 2025
End Date
July 31, 2026
Organizations
School of Dentistry  
Partner Organizations
National Science and Technology Council  
Project Web Site
https://www.grb.gov.tw/search/planDetail?id=18137294
Keywords
骨重塑
免疫微環境
穩定性
光生物調節
動物試驗
Description
本研究計畫預計以三年期將研究收集牙周
韌帶以及巨噬細胞於三維培養環境下受力學刺激後所釋放的細胞激素影響骨重
塑及骨免疫,並加入臨床用近紅外光進行研究,進行光敏性相關蛋白分子路徑評
估,並將藉由次世代定序全面性了解骨頭接受紅外光刺激所帶來的影響。最後再
以動物試驗模式來配合驗證。本計畫研究結果乃希望透過三維微環境之建立技術與機械力
及紅外光刺激之整合,提供給臨床齒顎矯正醫師未來在使用PBM 治療矯正後牙齒穩定性之參考。
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