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Chung Shan Medical University
Project/研究計畫(老師)
研究微核醣核酸調控 SIRT1 與相關調節路徑作為豨薟萃取物活性主成分奇壬醇改善重症肺炎疾病之分子機制
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研究微核醣核酸調控 SIRT1 與相關調節路徑作為豨薟萃取物活性主成分奇壬醇改善重症肺炎疾病之分子機制
Details
Primary Data
Project title
109學年度教學研究計畫
Acronym
教學研究計畫
Principal Investigator
關宇翔
Start Date
August 1, 2020
Organizations
College of Medicine
School of Medicine
Partner Organizations
National Science and Technology Council
Description
Keywords
奇壬醇
急性肺損傷
嗜中性球性氣喘
SIRT1
NFkB
p53
miR-7666
Description
計畫名稱:研究微核醣核酸調控 SIRT1 與相關調節路徑作為豨薟萃取物活性主成分奇壬醇改善重症肺炎疾病之分子機制
成果報告:
執行起迄:2020/08/01~2023/07/31
總核定金額:3,900,000元 (各年度經費明細)
計畫概述:內毒素脂多醣體 (LPS)存在於致病菌與空污細懸浮微粒表面,可誘發重症肺炎病,包括急性肺損傷 (ALI)、慢性阻塞性肺疾(COPD)、嗜中性球性氣喘。無良好治療策略的致病性肺炎已成為重要的醫療...(詳)
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