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Chung Shan Medical University
Project/研究計畫(老師)
具有缺氧標靶特性的光控藥物傳遞系統的開發與其在癌球幹細胞的偵測與治療上的應用
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具有缺氧標靶特性的光控藥物傳遞系統的開發與其在癌球幹細胞的偵測與治療上的應用
Details
Primary Data
Project title
106學年度國家科學及技術委員會補助研究計畫
Acronym
專題研究計畫
Principal Investigator
Chu, Chih-Chien
Status
research project
Start Date
2017
End Date
2018
Organizations
Department of Medical Applied Chemistry
Partner Organizations
National Science and Technology Council
Description
Keywords
香豆素
樹枝狀高分子
偶氮苯
藥物釋放
缺氧偵測
還原性酵素
癌症治療
Description
本年度計畫主要嘗試開發具有標靶缺氧特質的複合藥物傳遞與診斷系統。我們鎖定超過50%的癌細胞皆有過度表現的人類NQO1還原性酵素,開發出樹枝狀高分子衍生之螢光探針來分析此酵素在不同腫瘤細胞的表現...(詳)
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