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  2. Chung Shan Medical University
  3. Project/研究計畫(老師)
  4. 心血管疾病及骨質疏鬆交互作用機制探討
 
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心血管疾病及骨質疏鬆交互作用機制探討

  • Details
Project title
114學年度國家科學及技術委員會補助研究計畫
Acronym
專題研究計畫
Internal ID
NSTC114-2320-B040-011-MY3
Principal Investigator
Lee, Huei-Jane  
Status
research project
Start Date
August 1, 2025
End Date
July 31, 2026
Organizations
School of Medicine  
Partner Organizations
National Science and Technology Council  
Project Web Site
https://www.grb.gov.tw/search/planDetail?id=17975080
Keywords
心血管疾病
骨質疏鬆
血管鈣化
慢性心肌梗塞
血脂異常
系統性發炎
免疫反應
氧化壓力
心肌細胞
成骨細胞
破骨細胞
綠原酸
新綠原酸
Description
近年研究指出心血管疾病與骨質疏鬆可能會由共同或相似的病理機轉產生交互作用,增加心血管疾病與骨質疏鬆互相產生共病的風險並加成疾病嚴重程度。骨質疏鬆可能透過血管鈣化引起心血管疾病,心血管疾病也被指出有引起骨質疏鬆的可能。本計畫透過動物模型及細胞實驗探究共病交互作用,以及介入天然物的功能性成分研擬可施行的保健策略,有助於釐清機轉、使天然物功能性成分可以善加應用及降低醫療支出,預期具有學術、農業經濟及預防醫學之影響性。
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