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  2. Chung Shan Medical University
  3. Project/研究計畫(老師)
  4. RND家族菌種之螢光診斷技術及治療應用開發( II )
 
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RND家族菌種之螢光診斷技術及治療應用開發( II )

  • Details
Project title
114學年度國家科學及技術委員會補助研究計畫
Acronym
專題研究計畫
Internal ID
NSTC114-2113-M040-001
Principal Investigator
Chao, Chi-Min  
Status
research project
Start Date
August 1, 2025
End Date
July 31, 2026
Organizations
Department of Medical Applied Chemistry  
Partner Organizations
National Science and Technology Council  
Project Web Site
https://www.grb.gov.tw/search/planDetail?id=17965469
Keywords
多重抗藥性菌種
格蘭氏陰性菌
RND型外排幫浦
AcrB蛋白
基因選殖
螢光分子
喹唑啉酮
活性氧物質
Description
在當前臨床環境中,面對疑似多重抗藥性細菌感染的病患,醫療人員需進行檢體採集、菌種培養分析和分子生物學調查等程序,這通常需要數天時間。減少等待期並提供即時準確的信息對確保患者接受安全可靠治療及節省醫療資源至關重要。本計畫“RND家族菌種之螢光診斷技術及治療應用開發”旨在開發快速即時的診斷技術,並為殺菌治療展開先期研究,以增強對抗RND家族革蘭氏陰性菌多重抗藥性菌株的醫療反應,這種創新的螢光診斷技術目標為迅速確定多重抗藥性細菌,從而快速實施有效的消毒和治療措施,可以改善患者治療效果,降低廣泛感染的風險並減少醫療成本。
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