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  1. Home
  2. Chung Shan Medical University
  3. Project/研究計畫(老師)
  4. 以增強蛋白質清除機制緩解β類澱粉蛋白毒性為目標:探討GLP-1訊息之神經保護機轉
 
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以增強蛋白質清除機制緩解β類澱粉蛋白毒性為目標:探討GLP-1訊息之神經保護機轉

  • Details
Project title
109學年度教學研究計畫
Acronym
教學研究計畫
Principal Investigator
林志立  
Start Date
August 1, 2020
Organizations
College of Medicine  
Institute of Medicine  
Partner Organizations
National Science and Technology Council  
Keywords
亨丁頓舞蹈症
阿茲海默症
腸泌素訊息
胰島素訊息
蛋白質清除。
Description
計畫名稱:以增強蛋白質清除機制緩解β類澱粉蛋白毒性為目標:探討GLP-1訊息之神經保護機轉
成果報告:
執行起迄:2020/08/01~2021/07/31
總核定金額:1,000,000元 (各年度經費明細)
計畫概述:GLP-1是體內最主要的腸泌素,且大多數種類的中樞神經細胞都會表現出豐富的GLP-1受體,但其所造成的生理作用及分子機轉目前所知甚少。本研究將探討GLP-1訊息發揮神經保護作用的詳細機制,評估...(詳)
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