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  4. GAS5/GAS5-AS1透過競爭性結合RNA功能化於口腔黏膜下纖維化症之機制剖析及治療意涵
 
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GAS5/GAS5-AS1透過競爭性結合RNA功能化於口腔黏膜下纖維化症之機制剖析及治療意涵

  • Details
Project title
106學年度國家科學及技術委員會補助研究計畫
Acronym
專題研究計畫
Principal Investigator
Yu, Chuan-Hang  
Status
research project
Start Date
2017
End Date
2020
Organizations
School of Dentistry  
Partner Organizations
National Science and Technology Council  
Keywords
口腔黏膜纖維化症
GAS5
GAS5-AS1
肌纖維母細胞
Description
本研究鑑定出GAS5及GAS5-AS1於口腔頰黏膜纖維組織及其初代培養纖維化頰黏膜纖維母細胞低表達。GAS5-AS1過度表現可降低初代培養纖維化頰黏膜纖維母細胞及檳榔素誘發肌纖維母細胞活性。而...(詳)
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