Detecting the Dispersion of Bioaerosols Generated in Negative-Pressure Isolation Rooms

The good performance of NPIR rely on the compliance of negative differential air pressure (NDAP), air change rate per hour (ACH), and inward directional airflow (IDA) guidelines, and the study adopted and modified a biological test method to conduct performance and verification tests and thereby to demonstrate compliance with the physical containment requirements of NPIRs. Our work responds to the importance of investigating the performance of NPIRs about the suitable recovered bioaerosol concentration. Less bacteria-recovered concentration from NPIR will possibly lead to more NPIR construction cost, function inspection frequency or personal protection equipment used policy of health care workers. The study herein demonstrated a useful on-site bacteria generation and testing method to verify the function of those NPIRs even were used to control SARS-CoV-2 or any other airborne transmission diseases.