臺灣成年人運動習慣與高密度脂蛋白的相關性研究

研究目的：探討台灣成年人的有氧運動與羽球對高密度膽固醇(HDL-C)之影響。研究材料與方法：本研究為橫斷式研究(cross-sectional study)，資料取自中央研究院臺灣人體生物資料庫(Taiwan Biobank)，在2008-2016年間共有11346位年齡介於30-70歲參與者納入研究分析(女性6100人、男性5246人)。本研究透過運動習慣將參與者分成三組，分別是沒有運動、有氧運動及羽球，再進一步使用多變項線性迴歸模式(Multiple linear regression model)探討不同運動習慣對HDL的影響。所有模式中皆調整基因、年齡、生活習慣、體位測量指標及生化檢驗值等干擾因子。研究結果：本研究共有3819位規律運動者及7527位非規律運動者納入研究，其中，規律運動再細分成有氧運動(n=3775)及羽球(n=44)兩組。調整干擾因子後，以沒有運動習慣為參考組，本研究發現有氧運動與羽球皆顯著提高HDL-C，分別是有氧運動 (β =1.2838; P = <.0001)和羽球 (β = 4.7697; P = 0.0052)。結論與建議：有氧運動與羽球運動習慣與HDL-C 的提高有關，且羽球運動有更顯著的效果。

Elevated levels of high-density lipoprotein cholesterol (HDL-C) have been associated with a decreased risk of coronary heart disease (CHD). An active lifestyle is necessary in order to improve lipid HDL-C, including (but not limited to) physical exercise. Research on the association between badminton, an intermittent exercise, and HDL-C is limited. We investigated the impact of aerobic exercise and badminton on HDL-C levels in Taiwanese adults. The sociodemographic data of 11346 participants comprising 5246 men and 6100 women aged between 30 to 70 years were retrieved from the Taiwan Biobank. The participants were grouped into three exercise categories—no exercise, aerobic exercise, and badminton exercise. The HDL-C levels were compared using an analysis of variance (ANOVA). The multivariate linear regression models were used to determine the associations between HDL and exercise. Comparing the other two groups to the no-exercise group, the individuals who were engaged in aerobic and badminton exercise were significantly associated with a higher HDL-C (β=1.2839; p <0.0001 and β= 4.7697; p = 0.0052, respectively). Aerobic exercise and badminton were also associated with higher HDL-C levels among carriers of the lipoprotein lipase (LPL) rs328 genotypes. Aerobic exercise and regular badminton were associated with higher levels of HDL-C, with the badminton group being more significant.