過度LED光照所導致的視網膜病變

發光二極管(Light-emitting diodes, LED)的使用量在日常生活中日益上升，因其高效發光效能及低能源損耗在世界各國廣受歡迎，但LED所發出的白光比傳統鎢絲電燈泡包含更多的藍光，對眼睛有潛在性的傷害，然而其對人眼可能帶來的影響還未受到足夠重視。有研究發現高能量光波可對視網膜色素上皮 (Retinal pigment epithelium, RPE)造成損傷，在動物模型及細胞體外研究中已確立了基本的損傷通路。本文回顧相關文獻，以藍光LED對視網膜的影響為重心，探討先前相關研究成果，從而為日後研究提供思路。

Light-emitting diodes (LED) has gained more popularity in daily life worldwide, due to its high efficiency in light emission and low energy expenditure. Nevertheless, LED white lights contain more high energy blue lights than traditional Tungsten bulbs, which is potentially hazardous to human eyes. Despite that, there has been not enough attention on this issue. Previous reports have indicated that high energy lights may be detrimental to retinal pigment epithelium (RPE) and the mechanism of damages are established in animal models as well as in in vitro cell line studies. This assay reviews the related literature, focusing on the effects of blue lights on retina, so that some ideas may be concluded to guide for future researches.