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Week 96 Results of Switching from Tenofovir Disoproxil Fumarate-Based Antiretroviral Therapy to Coformulated Elvitegravir, Cobicistat, Emtricitabine, and Tenofovir Alafenamide among HIV/Hepatitis B Virus-Coinfected Patients
Journal
Microbiology Spectrum
Journal Volume
11
Journal Issue
3
ISSN
2165-0497
Date Issued
2023-06-15
Author(s)
Yu-Shan Huang
Chien-Yu Cheng
Hsin-Yun Sun
Shu-Hsing Cheng
Po-Liang Lu
Chen-Hsiang Lee
Hung-Chin Tsai
Chia-Jui Yang
Chun-Eng Liu
Bo-Huang Liou
Shih-Ping Lin
Sung-Hsi Huang
Mao-Wang Ho
Hung-Jen Tang
Chien-Ching Hung
Editor(s)
Yuan Pin Hung
Abstract
<jats:p>Elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide as a maintenance therapy showed durable and high rates of viral suppression for HIV/HBV-coinfected patients, with only 5.1% and 2.2% of patients having HBV DNA of ≥20 IU/mL and HIV RNA of ≥50 copies/mL, respectively, at 96 weeks. Our study fills the data gap on the long-term clinical effectiveness of tenofovir alafenamide-containing antiretroviral therapy in people living with HIV who have HBV coinfection.</jats:p>
SDGs
Publisher
American Society for Microbiology
Type
journal-article