佛手柑精油對肺癌細胞之潛在抗癌活性研究

佛手柑精油(Bergamia Essential Oils)具有萜類、醇類成分，如沉香醇可能具有化學預防特性，在本研究中，利用A549肺腺癌細胞株觀察佛手柑精油是否有抗腫瘤的潛力。首先，以DAPI染色、Annexin V/PI 雙染法用流式細胞儀偵測等，發現佛手柑精油明顯抑制A549細胞生長並且誘導細胞凋亡。並且以西方墨點法發現經佛手柑精油處理過後會去抑制NF-κB的磷酸化表現。綜合以上結果，佛手柑精油會去誘發細胞凋亡，可視為在癌症治療及預防中有效的醫療資源。

Bergamot essential oil contains terpenes and the compositions of alcohol such as linalool which may possess chemoprvention properties. In this study, I adopt the methods as DAPI staining, Annexin V /P double staining and western blot, etc. The results show Bergamot essential oil will induce apoptosis, that can be considered effective in cancer treatment and prevention of medical resources.