攝護腺移形區指數于良性攝護腺肥大的重要性

目的：對於有下泌尿道症狀之良性攝護腺肥大(Benign Prostatic Hyperplasia; BPH)患者，闡述攝護腺移形區指數於良性攝護腺肥大患者之臨床應用。材料與方法：自2002年1月至2002年6月，共42名有BPH臨床症狀初診患者參與此項研究。利用經直腸超音波(Transrectal Ultrasound; TRUS)測量出攝護腺總體積(Prostate Volume; PV)、移形區體積(Transition Zone Volume; TZV)，並計算出移形區指數(Transition Zone Index; TZI)之數據；並且與最大尿流速(Maximal Flow Rate; Qmax)進行相關性研究之統計分析。結果：攝護腺移形區指數與攝護腺總體積有顯著相關(r=0.423, p<0.01)；攝護腺移形區指數與最大尿流速有顯著相關(r=-0.502, p<0.01)。結論：本研究結果顯示，TZI和患者的Qmax有顯著相關(p<0.01)。因此對於良性攝護腺肥大患者臨床阻塞症狀之評估，尤其當病患要接受手術治療時，TZI與Qmax可以提供良好的資訊；更可以當作一個很好的指標。因此對於良性攝護腺肥大患者之探討，TZI是一個良好的特異性指標，值得我們更進一步的研究。
Purpose: To elucidate clinical application of Transition Zone Index (TZI)in benign prostatic hyperplasia (BPH) patients with lower urinary tract symptoms. Materials and Methods: From January 2002 to June 2002, 42 patients with symptomatic BPH were enrolled in this study. All subjects underwent transrectal ultrasound (TRUS) for prostate volume (PV), transition zone volume (TZV)and transition zone index(TZI). The measurements of volume were compared statistically with maximal flow rate (Qmax). Results: There was a significant correlation between of TZI and PV (r=0.423, P<0.01) and between TZI and Qmax (r=-0.502, P<0.01). Conclusion: These studies find a significant correlation between TZI and Qmax (P<0.01). TZI and Qmax provided important information about the clinical obstructive symptoms in patients with BPH, especially for those needing further surgery. TZI was found to be a good specific index in the elucidating the clinical characteristics of BPH.