Relationship of Follicle Number and Sperm Parameter to Pregnancy Rate in Different Ovulation Induction Protocol Induced Intrauterine Insemination Cycles

The aim of the present study was to evaluate whether the induction of multiple ovulation can increase the pregnancy rates in couples treated with AIH. 624 couples underwent a total of 1242 cycles of IUI with husband's sperm after ovarian stimulation with clomiphene citrate (CC)-human gonadotropin combination or human gonadotropins alone. We Compared the follicle numbers of induction by CC, CC/hMG, with the pregnancy rates, and the outcome of three stimulation protocols with washed husband's sperm of different parameter. This figure was significantly higher pregnancy rates in ovulation stimulation groups (15.6%) than natural group (8.3%). On the other hand, we also get satisfied results of oligospermia group (10.8%) and asthenospermia group (11.5%) after ovarian stimulation. However, there was still low pregnancy rates in the oligospermia groups (3.0%). It is therefore suggested that a trial of induction of multiple follicular development may be perfromed in couples with male-related before their inclusion in protocols for advance procedures, such in vitro fertilization (IVF) or intracytoplasmic sperm injection(ISCI).