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  1. Home
  2. College of Medical Science and Technology/醫學科技學院
  3. Department of Medical Laboratory and Biotechnology/醫學檢驗暨生物技術學系
  4. 微生物群:在人類健康、檢測和保健產品中的作用
 
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微生物群:在人類健康、檢測和保健產品中的作用

Date Issued
2020
Author(s)
黎偉華
Wai-Wa Lai
Advisor
蔡淦仁
葉千紅
Kan-Jen Tsai  
Qian-Hong Ye
URI
https://handle.ncl.edu.tw/11296/gfpfct
https://scholars.csmu.edu.tw/handle/123456789/22176
Abstract
腸道中的各種各樣微生物,在人體的腸道中型成一個小型獨立的生態系統,這個生態系統有自己的平衡,這個平衡一旦打破,影響不單單是腹瀉,還會通過腸-腦軸造成精神行為上的間接影響。許多的精神疾病研究關注的地方開始關注腸道微生物群,有研究指出許多精神疾病患者也有腸道微生物群失調的情況,可能是某一種菌種缺乏,而且精神狀況的影響是雙向的,會有病患本身的腸道微生物群缺少而引致病發,也有是由於患病而慢慢導致腸道微生物群減少而失衡,目前的研究都集中在這一方面。腸道微生物群的另一個研究方向是檢測方法,目前雖有許多不同的方法可以進行檢測,但各有優劣。結論︰目前腸道微生物群的研究有許多的限制,主要是因為取樣的方式有一定的影響,人體實驗也具有風險,外國更有一例進行糞便移植的病人死亡,目前主要集中在研究精神疾病與腸道微生物群的關係,以及益生菌對腸道微生物群的作用。
The various microorganisms in the intestine form a small independent ecosystem in the human intestine. This ecosystem has its own balance. Once this balance is broken, the impact is not only diarrhea but also the spirit through the intestine-brain axis Behavioral indirect effects. Many psychiatric studies have begun to focus on intestinal microbiota. Some studies have pointed out that many patients with mental illness also have dysregulation of intestinal microbiota. It may be that a certain type of bacteria is lacking, and the impact of mental status is bidirectional The lack of intestinal microbiota in the patient itself leads to the occurrence of disease. There are also cases where the intestinal microbiota is slowly reduced due to illness and is unbalanced. The current research is focused on this aspect. Another research direction of intestinal microbiota is the detection method. Although there are many different methods of detection, there are advantages and disadvantages. Conclusion: At present, there are many restrictions on the study of intestinal microbiota, mainly because the sampling method has a certain impact, and human experiments are also at risk. Another case of feces transplantation in foreign countries has died. At present, the main focus is on the study of mental illness and The relationship between the gut microbiota and the effect of probiotics on the gut microbiota.
Subjects
腸道微生物群
精神疾病
益生菌
糞便移植
intestinal flora
mental illness
probiotics
fecal transplantation
Type
thesis
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108CSMU5108025-001.zip

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