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  4. Radiation dose for normal organs by helical tomotherapy for lung cancer
 
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Radiation dose for normal organs by helical tomotherapy for lung cancer

Journal
Applied Radiation and Isotopes
Date Issued
2015-08-01
Author(s)
HSIEN-CHUN TSENG  
CHIEN-YI CHEN  
DOI
10.1016/j.apradiso.2015.04.007
URI
https://www.scopus.com/pages/publications/84928616989
https://scholars.csmu.edu.tw/handle/123456789/23253
Abstract
This study derived a simple equation of effective dose (E) versus normal organ of patients with varying body weights undergoing lung cancer treatment of helical tomotherapy (TOMO). Five tissue-equivalent and Rando phantoms were used to simulate lung cancer patients. This study then measured E and equivalent dose of organ or tissues (DT) using thermoluminescent dosimetry (TLD-100H). The TLD-100H was calibrated using TOMO 6MV photons, then inserted into phantom positions that closely corresponded with the position of the represented organs and tissues. Both E and DT were evaluated by ICRP 103. Peripheral doses varied markedly at positions close to the tumor center. The maximum statistical and total errors were 16.7-22.3%. This analytical result indicates that E of Rando and tissue-equivalent phantoms was in the ranged of 9.44±1.70 (10kg) to 4.58±0.83 (90kg)mSv/Gy. Notably, E decreased exponentially as phantom weight increased. Peripheral doses were also evaluated by TLD as a function of distance from the tumor center. Finally, experimental results are compared with those in literature. These findings will prove useful to patients, physicians, radiologists, and the public.
Type
journal article
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