Hb Tak

Other Title
A β chain elongation at the end of the β chain, in a Taiwanese
Journal
Hemoglobin
Date Issued
2005-01-01
Author(s)
DOI
URI
Abstract
Hemoglobin (Hb) variants caused by an elongation of the β-globin chain are rare. In this study, we present the first case of Hb Tak in a Taiwanese. Hb Tak is caused by an insertion of the dinucleotides AC into codon 146 that abolishes the normal stop codon at position 147. This insertion results in a frameshift causing elongation of the β chain by 11 amino acids.
Type
journal article