介入富含乳清蛋白管灌配方對腦中風及創傷性腦損傷病人復健之成效

The possible risk of malnutrition in patients with central nerve system injuries (CNSIs) compromises the prognosis of rehabilitation; such patients may have sequelae such as limb hemiplegia, cognitive dysfunction, and chewing and swallowing dysfunction after emergent resuscitation. Effects of a whey protein-enriched formula in increasing the muscle mass and functional performance were examined in this study. CNSI inpatients in a rehabilitation department received five doses/day of a whey protein-enriched formula in addition to regular formula and an oral diet while undergoing swallowing training. The target total calories was 30 kcal/kg body weight (BW)/day, total protein was 1.4 g/kg BW/day, and the study period was 28 days. The nutritional intake was carefully recorded. Data from the start and end of study were analyzed with paired t-test. Fifty CNSI patients were enrolled. The average age was 64.6±15.02 (mean±SD) years. The total score of the Mini Nutrition Assessment (MNA) increased from 18.6±3.78 to 21.4±2.93 (p<0.001), the arm circumference changed from 26.5±3.01 to 27.0±3.07 cm (p=0.009), the calf circumference increased from 31.3±3.23 to 31.6±3.08 cm (p=0.015), the muscle mass changed from 42.0±7.40 to 42.7±7.05 kg (p=0.029), the bone mass increased from 2.37±0.37 to 2.41±0.34 kg (p=0.042), and functional independence measure (FIM) score, which indicated improved rehabilitation exercise performance, changed from 42.9±13.6 to 49.7±16.07 (p<0.001). The effects of high protein combined with the whey protein supplementary nutrition intervention formula on the nutritional status, muscle mass, and function of CNSI patients were promising.