以文獻計量學分析三叉神經心臟反射在牙醫領域刊登之論文研究

三叉神經心臟反射(Trigeminocardiac reflex; TCR)是一種腦幹反射，其特徵是三叉神經受到刺激後出現突發性心搏徐緩低血壓和其他副交感神經反應。目前有關三叉神經心臟反射之研究文獻已在醫學領域有所探討，然而針對牙科領域的研究報導仍相當有限。因此本研究使用文獻計量學(bibliometric analysis)分析三叉神經心臟在牙科領域發表文章的趨勢和影響。從2001年1月1日到2024年12月31日止，以關鍵詞“Trigeminocardiac reflex”或“trigemino-cardiac reflex”或“trigeminal cardiac reflex”或“severe bradycardia”或“diving reflex”或“oculocardiac reflex”在Web of Science核心資料庫中進行搜尋，共探索獲得1007篇文獻。排除與牙科領域無關之文獻後，最終收錄52篇相關牙科領域文獻進行分析。本研究使用Excel和VOSviewer製作視覺化圖表和網路地圖來進行描述統計分析，來呈現三叉神經心臟反射在牙科領域研究之現況。結果顯示，46%為原著文章(original article)，25%為致編者信(letters to the editor)，10%為文獻綜述(review)。總共引用次數排名前十的文章包括原著文章七篇和文獻綜述三篇。從國別來看，如義大利發表了10篇文獻等。根據本研究納入52篇文章的研究結果，三叉神經心臟反射的主要誘發因素分別為顎面手術(maxillofacial surgeries)、延長或强迫張口(prolonged or forced mouth opening)及拔牙(dental extractions)。總結，本研究將有助於釐清三叉神經心臟反射在牙科領域之研究現況，提醒牙科醫師此反射的存在以及重要性，也可作為未來牙科臨床應用與研究方向的參考依據。

The trigeminocardiac reflex (TCR) is a brainstem reflex characterized by sudden bradycardia, hypotension, and other parasympathetic responses following stimulation of the trigeminal nerve. While TCR has been explored in medical literature, studies within the field of dentistry remain limited. This gap highlights the need for a systematic evaluation of the relevant literature. Therefore, this bibliometric analysis aims to examine the scope, trends and impact of research on TCR in dentistry. A comprehensive search from January 1, 2001 to December 31, 2024, was carried out in the Web of Science (WOS) Core Collection database (Clarivate Analytics). The search terms included “Trigeminocardiac reflex” OR “trigemino-cardiac reflex” OR “trigeminal cardiac reflex” OR “severe bradycardia” OR “diving reflex” OR “oculocardiac reflex”, and a total of 1007 articles were retrieved. Publications not related to the field of dentistry were excluded, resulting in 52 publications for analysis. Descriptive statistical analyses were performed using Excel, while visual graphs and network maps were generated using VOSviewer. Results showed 46% of the publications were original articles, 25% were letters to the editor, and 10% were reviews. The top 10 articles included seven original articles and three literature reviews. Italy ranked first with 10 publications. Based on the findings from the 52 articles, the most frequently reported triggers for TCR included maxillofacial surgeries, prolonged or forced mouth opening, and dental extractions. In conclusion, this study may help to clarify the current state of research on the TCR in the field of dentistry and to also inform dentists of the existence and significance of TCR.