孕婦與巨細胞病毒及弓漿蟲感染之調查研究

在此研究中，為瞭解湖北省武漢地區孕婦受巨細胞病毒及弓漿蟲感染的情形，我們以酵素免疫分析法， 檢查 617 位懷孕三個月至六個月健康孕婦的巨細胞病毒及弓漿蟲的抗體。 結果發現巨細胞病毒 IgG 抗體陽性者在 617 位孕婦中有 578 人佔 93.7%，IgM 抗體陽性者有 78 人佔 12.6%。其結果，顯示武漢地孕婦對巨細胞病毒抗體 IgG 及 IgM 之陽性率均高於已開發國家，新生兒的先天感染，主要可能是由受感染的孕婦垂直感染引起。所以對懷孕婦女建立預防計畫是很重要的。在同樣地區也用同樣方法研究弓漿蟲感染。在這研究中，發現弓漿蟲 IgG 抗體陽性率非常低 (0.6%)，顯示這地區孕婦容易受弓漿蟲的感染，自然地也就增加母體垂直感染的可能性。所以應該實施適當地預防及治療計畫，避免此地區孕婦感染弓漿蟲的可能性。
In this study, we have investigated the prevalence of Human Cytomegalovirus (HCMV) and Toxoplasma gondii (T. gondii) infections among the pregnant women in Wu-Han, China. A total of 617 healthy women during their third to sixth month of pregnancies were studied and their antibody statuses to both HCMV and T. gondii were measured using the enzyme immunoassay methods. Among these pregnant women, 578(93.7%) or 78(12.6%) were positive in either IgG or IgM antibodies to cytomegalovirus. These results are higher than those studies performed in other developed countries. Since most of the newborn infections are possibly due to the direct infection from their re-infected mothers, therefore, it will be considerably important to establish a prevention program for the pregnant women. Similar studies have been conducted to investigate T.gondii infections in the same area. In this study, a very low T. gondii IgG positive rate (0.6%) was found. Indicating that the pregnant women in this area are vulnerable for T. gondii infections and consequently increased in the possibility for the direct materanl infections. Therefore, a proper prevention and treatment program should be implemented to avoid the possible T. gondii infections to the pregnant women in this area.