陳健懿Chien-Yi Chen樂瑩怡Ying-Yi Le醫學影像暨放射科學系2026-03-269999-12-3120202020-08-10https://handle.ncl.edu.tw/11296/6dsgfrhttps://scholars.csmu.edu.tw/handle/123456789/7533背景：同位素治療中心(Isotope Therapy Center, ITC)於2019年5月在台灣中山醫學大學附設醫院(Chung Shan Medical University, CSMUH)核子醫學科(Nuclear Medicine department, NM)建成。目的：由於新的同位素治療中心的運行，有必要評估NM中環境暴露的可能增加。方法：使用131I對TLD進行校準，確保其誤差小於10％。藉由田口最佳化方法調整TLD計讀參數，提高準確度。使用經篩選準確且靈敏的TLD-100H對ITC中的環境輻射進行了為期兩天的九次評估。結果：經由田口最佳化實驗得到初始溫度為135°C，加熱時間為10°C / s，最高溫度為240°C，預熱時間為10 s為本實驗所用之TLD最佳計讀參數。在ITC碘-131病房內檢測到的暴露輻射範圍為2.376±0.091至0.003±0.001 mSv / h，表明碘-131病房的輻射存在顯著差異。本研究應用田口方法在儀器調整參數並選定最佳化調整組合，然後確認驗證，以驗證實驗的再現性。本文還討論了環境輻射的最小可檢測劑量，以證明該方法的可靠性。 結論：這項研究表明ITC對核醫科沒有額外的輻射危害。BACKGROUND: Isotope Therapy Center (ITC) were built in May 2019 at the Nuclear Medicine Department (NM) of Chung Shan Medical University Hospital (CSMUH) at Taiwan.OBJECTIVE: It is necessary to evaluate a possible increase in the environmental gamma exposure rates in the NM as a result of the operation of the new Isotope Therapy Center.METHODS: The TLDs were calibrated using known activities of 131I capsule. A two-day nine times evaluation of environmental radiation in the ITC was performed using the accurate and sensitive TLD-100H method, which gives an error less than 10%. In this study, the Taguchi method was used to adjust the parameters of the instrument and select the optimal adjustment combination, and then confirm the verification to verify the reproducibility of the experiment.RESULTS: Our analysis indicates that 135 °C for the initial temperature, 10 °C/s for the heating time, 240 °C for the max temperature and 10 s for the preheat time are the best choice in terms of image quality. The exposure radiation detected in the ITC iodine-131 ward ranged from 2.376±0.091 to 0.003±0.001 mSv/h, indicating that there was a significant difference in the radiation of the iodine-131 ward. In this study, the Taguchi method was used to adjust the parameters of the instrument and select the optimal adjustment combination, and then confirm the verification to verify the reproducibility of the experiment. This article also discusses the minimum detectable dose of ambient radiation to prove the reliability of TLD-100H.CONCLUSION: This study demonstrated there are no extra radiation hazards among NM.田口方法環境輻射同位素治療中心熱發光劑量計碘-131最小可測值Taguchi methodEnvironmental RadiationIsotope Therapy CenterThermoluminescence dosimeterI-131Minimum detectable dosethesis