TSU-MAN CHIU2026-10-162026-10-162022-02-17Pure ID: 15022918Pure UUID: 5ba271e9-1fa5-4854-a9c0-d51bd023648910.3389/fped.2021.802715https://www.scopus.com/pages/publications/85125862566https://scholars.csmu.edu.tw/handle/123456789/28836Diclofenac is one of the most commonly used non-steroidal anti-inflammatory drug (NSAID) agents for fever management by general practitioners. Anaphylaxis due to suppository of diclofenac sodium (Voltaren) is extremely rare in children. We report the case of a 3-year-old girl with anaphylactic shock after a diclofenac suppository with confirmation by serial tryptase and a basophil activation test.enjournal article