The protective effects of beta-mangostin against sodium iodate-induced retinal ROS-mediated apoptosis through MEK/ERK and p53 signaling pathways

Yuan-Yen ChangMeilin WangJui-Hsuan YehShang-Chun TsouTzu-Chun ChenMin-Yen HsuYi-Ju LeeInga WangHui-Wen Lin2026-02-032026-02-03202310.1039/d3fo03568ahttps://scholars.csmu.edu.tw/handle/123456789/4863Previous studies have indicated that NaIO3induces intracellular reactive oxygen species (ROS) production and has been used as a model for age-related macular degeneration (AMD) due to the selective retinal pigment epithelium (RPE) cell damage it induces.The protective effects of beta-mangostin against sodium iodate-induced retinal ROS-mediated apoptosis through MEK/ERK and p53 signaling pathwaysjournal-article