2026-11-092026-11-09https://scholars.csmu.edu.tw/handle/123456789/38207Nelumbo nucifera Gaertn. (Nymphaeaceae) is a large aquatic herb widely found in India and Taiwan. Traditional medicinal systems advocate several different therapeutic effects of this herb (1). The rhizome is considered to be nutritive, demulcent, diuretic and cholagogue and is used to treat piles, dyspepsia and diarroea. Different pharmacological and antimicrobial activities of the methanol extract of the rhizomes, including antidiarrhoeal (2) psychopharmacological (3), diuretic (4) , antipyretic (5), antibacterial (6) and antifungal (7) potentials have been reported previously. The powdered rhizomes are prescribed for piles as demulcents, beneficial in dysentery and chronic dyspepsia (4). In recently research finger out, Nelumbo nucifera leaf has antioxidative ability (8), thus, we want to known whether Nelumbo nueifera has any other biomedical function by its anti-oxidative ability.&#13;&#10;<BR>The aim of this study was to evaluate the effects of lotus leaf on plasma lipids in rabbits affected by experimental atherosclerosis induced by the intake of high cholesterol diet. The importance of the research might be to provide evidence about the anti-atherogenic evidence of specific dietary components. In this sense, there is a paucity of studies about the effects of curcuma on atherosclerosis and on its possible use in the prevention of cardiovascular diseases.國人罹患心血管疾病之比例甚高，其成因相對複雜，包括高膽固醇、LDL氧化、smooth muscle cell及發炎細胞的凋謝死亡等因素。若能發展一無副作用的天然食品具有(1)降血脂；(2)抑制LDL氧化；(3)抑制血管病變。&#13;&#10;<BR>&#13;&#10;<BR>2.荷葉盛產於本省中南部及東部，易栽培且食用上無副作用，並含有許多多酚酸成分，具有抗氧化、防癌及抑制高血脂之作用，因此可發展為預防心血管疾病之保健食品，以減少國人罹患心血管疾病之風險及提高其農產價值。在本實驗室先前開發洛神花之模式下，相信可利用已建立之試驗模式為荷葉萃取物進行分析研究，進一步推廣為保健食品，以利國人加強攝食荷葉製品，預防心血管疾病並推廣農產品之應用，增進農產經濟。荷葉血脂動脈硬化低密度脂蛋白氧化Lotus LeafSerum LipidAtherosclerosisLDL OxidationProject