2026-11-092026-11-09https://scholars.csmu.edu.tw/handle/123456789/38667In resent years, domestic medical center pushed to assemble helical TomoTherapy in order to treat head and neck cancers (HNC). The TomoTherapy of Chung Shan Medical University Hospital (CSMUH) (TomoTherapy, Madison, WI, USA) consists of linear accelerator (linac) mounted onto a computed tomography (CT) ring gantry undergoing Image Guided Radiotherapy (IGRT). This system is operational as therapeutic delivery system and an imaging system. However, running TomoTherapy will generate high energy x-rays. These x-ray doses to the total body of patients from scattering and leakage radiation from primary exposure of therapy are not detailed in routine treatment planning. But it is important for better estimates of health risks. There is limited data currently available for making leakage radiations and risk assessments for adult patients at Taiwan. The project (1) the first year is to optimize various TomoTherapy doses via TLD-100 using the Taguchi method. (2) Rando and a set of self-developed phantoms in the range of patient sizes from 50 to 90 kg to measure effective dose using thermoluminescent dosimeters, TLD-100 in the second years. (3) For comparing the x-ray dose, MCNP (Monte Carlo Neutron Photon) code (BodyBuilder) will be simulate the HNC does of TomoTherapy in the third years. This work will develop to correlate the risk-related quantity to the more simply derived quantity mass-doses. These involved scanning a series of adult anthropomorphic phantoms containing measure effective dose for therapy of various anatomic regions. This work also identifies radioactive hot spots of Medical Univ. TomoTherapy to which advisory for radiation protection can be assessed at Taiwan.國内各醫學中心近年來加快裝設導航螺旋光子刀(TomoTherapy) ’進行頭頸部癌症 治療（head and neck cancers, HNC)，中山醫學大學附設醫院之TomoTherapy (TomoTherapy, Madison, WI, USA)具有直線加速器(linear accelerator, linac)配合電腦斷 層掃描(computed tomography, CT)進行影像導航式放射治療(Image Guided Radiotherapy, IGRT)。惟運轉中的直線加速器會有巨量高能x-ray自靶區散射並洩漏輻射外釋，造成患 者的劑量大幅增加，且這些並不是治療計畫的一部份，實不得不加以詳查。本三年計畫 擬以(1)第一年以田口式方法得到熱發光劑量計TLD-100 (thermoluminescence dosimety, TLD)於TomoTherapy頭頸部癌症治療劑量上的最佳化量測條件。（2)第二年以命道 (Rando)及重量50至90公斤之自行研發擬人型假體，佈植TLD-100來測量估算等效劑 量，以求得不同體重下病人與輻射關係，這可望推廣應用至全國各大醫學中心（3)第三 年以蒙地卡羅軟體MCNP code (BodyBuilder)模擬患者輻射劑量分布，劑量上的比較， 而對日後國内各大學醫學中心之Hi-Art TomoTherapy，提出患者必要的輕射防護建議。導航螺旋光子刀洩漏輻射田口式方法熱發光劑量計自行研發假體蒙地卡羅模擬TomoTherapyLeakage radiationTaguchi methodTLDSelf-developed phantomMCNPProject