沈祐成You-Cheng Shen翁憶華Yi-Hua Weng健康產業科技管理學系碩士班2026-03-232024-08-3020242024-07-26https://handle.ncl.edu.tw/11296/6772j3https://scholars.csmu.edu.tw/handle/123456789/6315本研究旨在探討輔酶Q10補充對體能與協調性能力的影響，特別是其在不同性別、年齡段及血液輔酶Q10濃度不同的受測者中的效果。本研究共招募了22位年齡介於7至21歲的受測者，其中包括10位女性和12位男性，受測者根據體重每公斤補充10毫克輔酶Q10，最高600毫克，進行為期13週的輔酶Q10補充試驗。受測者在試驗前、後接受了BOT-2測試，以評估輔酶Q10補充前、後在雙側協調、平衡、身體協調、跑步速度與敏捷度、力量及力量和靈活性六個體能項目的表現變化。研究結果顯示，輔酶Q10補充對所有受測者在六個測試項目中的表現均有顯著改善，p值均小於0.05，顯示輔酶Q10對受測者的整體體能和協調性有明顯的增強效果。女性受測者在所有項目中均表現出顯著的進步，尤其是在平衡和身體協調方面；男性受測者則在雙側協調、平衡和跑步速度與敏捷度項目中有顯著提升，唯獨在力量項目中未達顯著性差異。此外，4位年齡超過21歲的受測者在精細動作控制和身體協調方面也顯示出顯著改善，而其他項目未達顯著性。特別值得注意的是，10位血液輔酶Q10濃度低於健康樣本的受測者在所有測試項目中均顯示出顯著的進步，特別是在平衡、身體協調及跑步速度與敏捷度方面，進一步證實輔酶Q10對於血液濃度低下者具有更為顯著的效果。此外，本研究也探討了輔酶Q10補充對受測者主要照顧者壓力的影響，結果顯示照顧者在試驗後的壓力感顯著降低，尤其是在身體不適感、疲倦感、體力負擔及情緒負面影響等方面，p值均小於0.05。這表明輔酶Q10補充不僅對受測者的體能和協調能力有明顯幫助，還能有效減輕照顧者的壓力，提高其生活品質。總結來說，本研究證實了輔酶Q10對體能、協調性及照顧者壓力的顯著改善效果。然而，樣本量較小及研究時間較短是本研究的限制。未來研究應擴大樣本範圍，涵蓋不同年齡段及健康狀況的受測者，並進行長期隨訪，以全面了解輔酶Q10的作用機制及其臨床應用潛力。This study aimed to investigate the effects of Coenzyme Q10 (CoQ10) supplementation on physical fitness and coordination abilities, particularly across different genders, age groups, and baseline blood CoQ10 levels. A total of 22 participants aged 7 to 21 years, including 10 females and 12 males, were enrolled in the study. Participants received a CoQ10 supplementation dose of 10 mg per kilogram of body weight, with a maximum of 600 mg, over a 13-week period. Participants underwent BOT-2 testing before and after the trial to assess changes in performance across six physical fitness domains: bilateral coordination, balance, body coordination, running speed and agility, strength, and strength and agility. The results showed significant improvements in all six testing areas following CoQ10 supplementation, with p-values below 0.05, indicating a notable enhancement in overall physical fitness and coordination. Female participants exhibited significant progress in all tested areas, particularly in balance and body coordination. Male participants also showed substantial improvements in bilateral coordination, balance, and running speed and agility, although strength did not reach statistical significance. Additionally, four participants over 21 years old demonstrated significant improvements in fine manual control and body coordination, though other areas did not achieve statistical significance. Notably, the 10 participants with baseline blood CoQ10 levels below the healthy range exhibited marked improvements in all testing areas, particularly in balance, body coordination, and running speed and agility, further confirming the more pronounced effects of CoQ10 supplementation in individuals with lower baseline levels.Furthermore, the study also examined the impact of CoQ10 supplementation on the stress levels of primary caregivers. The results revealed a significant reduction in caregiver stress after the trial, especially in areas such as physical discomfort, fatigue, physical burden, and emotional impact, with p-values below 0.05. This suggests that CoQ10 supplementation not only significantly benefits the physical fitness and coordination of participants but also effectively reduces caregiver stress, thereby improving their quality of life.In conclusion, this study confirms the significant benefits of CoQ10 supplementation on physical fitness, coordination, and caregiver stress. However, the limitations of a small sample size and short study duration should be noted. Future research should expand the sample size to include participants of different age groups and health conditions, and conduct long-term follow-ups to gain a comprehensive understanding of the mechanisms and clinical potential of CoQ10 supplementation.運動協調威廉斯氏症候群(Williams SyndromeWS)輔酶Q10平衡力量Motor CoordinationWilliams Syndrome (WS)Coenzyme Q10BalanceStrengththesis