2026-09-302026-09-30https://scholars.csmu.edu.tw/handle/123456789/19546The Kv7 protein openers are a new group of potential clinical neurological disease therapy in recent years. In this study, we develop a group of Kv7 protein opener derivatives (21 compounds) to in...(詳)Kv7蛋白開啟劑是近年來新發展的一群很有潛力的神經疾病治療用藥物。本實驗中我們開發出一群Kv7蛋白開啟劑的衍生物(21種)來探討他們在小鼠中運動神經的作用,其中我們發現大部分的衍生物並無Kv7...(詳)關鍵詞Kv7蛋白Kv7 開啟劑鈉波峰阻斷劑類lidocaine效應局部麻醉劑。Key WordsKv7 proteinKv7 openerssodium spike inhibitorlidocaine-like effectlocal anesthetic agents探討新開發之 AM- mesitylglycinamide化合物對於KCNQ蛋白之作用機轉與其可能的應用Project