2026-11-092026-11-09https://scholars.csmu.edu.tw/handle/123456789/38075The Chinese yam is known for its high nutrition, low calorie and multi healthcare effects. It is extremely rich in its natural plant hormones and saponins. Other than its abundant supply of glucose and mineral resources, it also contains a great number of ingredients that are biologically active. The current research plans to use the female Wistar rat as the experimental animal. Randomly categorize the rats into the experimental group (ovary removed after surgery) and the comparison group (ovary kept after surgery) to establish the menopause animal mode. Both groups of rats will recovery for four weeks after the surgery. Using the open field test and the elevated plus-maze test, rats are further arranged into four groups according to the different levels of anxiety (comparison groups into three); they will be fed with different dosages of yam (Dioscorea L. alata. Var. purpurea (Roxb.) M. Pouch, from Nantou county). Continue for four weeks then sacrifice the animal to remove their two femurs. Then use DEXA to run a bone mineral content test to the femur, one side of the femur will be tested for the related bone mass, porosity, bone mineral density and physic parameter surveys and calculations. The other side of the femur will be tested for material tests. This project will obtain how yam affects the skeletal physic parameter of the controlled and comparison groups, and the effects of different dosages of yam in the controlled group (menopause animals) and the comparison group (non-menopause animals), and suggestions for appraising the skeletal features' feasibility flow.山藥為已知具備高營養、低熱量及多重保健功效之植物；其天然植物性賀爾蒙及皂甘成分含量非常豐富。它除了富含澱粉及礦物質之外，還含有許多具有生理活性的成分。本計畫擬以雌性Wistar大鼠為實驗動物，將動物隨機分為實驗組(切除卵巢)及對照組(手術但保持卵巢完整)以建立停經動物模式。手術後使其恢復四周，再以開放空間及高腳十字迷宮試驗結果，將具有不同焦慮程度之實驗鼠均勻分配於四組(對照組為三組)，餵食不同的山藥劑量(取南投名間鄉紫田薯)。持續四周後將動物犧牲並取下兩側股骨。再以DEXA對股骨進行骨礦物質含量之檢測，其中一側股骨進行相關之骨體積、孔隙率、骨礦物質密度等物理參數測量及計算，並將另一側股骨進行材料試驗。 本計畫將可以獲知山藥對實驗組與對照組之骨骼物理參數之影響性、山藥劑量之多寡對實驗組(停經動物)之骨骼參數影響性、山藥劑量對對照組(非停經動物)之骨骼參數影響性、以及建議骨骼特性之可行評估流程。山藥骨質疏鬆骨密度停經DioscoreaOsteoporosisBone DensityMenopauseProject