PUI-YING LEONGJAMES CHENG-CHUNG WEI2026-10-162026-10-162016-02-01Pure ID: 15130896Pure UUID: 1dfd8416-7a71-402e-b1ab-8ad15a161a5110.6314/JIMT.2016.27(1).04https://www.scopus.com/pages/publications/84969263290https://scholars.csmu.edu.tw/handle/123456789/25847Systemic sclerosis (scleroderma; SSc) is a chronic multisystem autoimmune disease characterized by a vasculopathy which divided into limited cutaneous disease and diffuse cutaneous disease. The clinical manifestations of this disease are diffuse fibrosis of skin and multiple internal organs. A newly diagnosed criterion was established by American College of Rheumatology (ACR) and The European League Against Rheumatism (EULAR) in 2013. Compare to ACR 1980 criteria, it included capillary microscopy evaluation and scleroderma specific autoantibody and provided higher sensitivity and specificity. This review discusses the newly diagnostic criteria, capillary microscopic vascular pattern, newly therapeutic recommendations and developing assessment tools for scleroderma.10enjournal article