CHIN-TE HUANG2026-10-162026-10-162015-05-27Pure ID: 15447939Pure UUID: 48e7c6b7-97a9-4946-8a2a-dc13eb2eb0f710.2147/OPTH.S79697https://www.scopus.com/pages/publications/84930650643https://scholars.csmu.edu.tw/handle/123456789/30758Epidemic viral conjunctivitis is a highly contagious disease that is encountered year-round. The causative agents are mainly adenoviruses and enteroviruses. It occurs most commonly upon infection with subgroup D adenoviruses of types 8, 19, or 37. For common corneal involvement of human adenovirus type 8 epidemic keratoconjunctivitis, full-layer epithelial detachment is rarely seen. Herein, we report three cases of epidemic keratoconjunctivitis during an outbreak which manifested as large corneal epithelial full-layer detachment within a few days. The lesions healed without severe sequelae under proper treatment. The unique manifestation of this outbreak may indicate the evolution of human adenovirus type 8.5enHuman adenovirus type 8 epidemic keratoconjunctivitis with large corneal epithelial full-layer detachmentAn endemic outbreak with uncommon manifestationsjournal article