2026-11-092026-11-09https://scholars.csmu.edu.tw/handle/123456789/38577Clinical studies on artificial hip joint had shown that the biological failure is a result of osteolytic reactions to the wear debris in bone tissue surrounding the prosthesis, which often lead to the loosening of the prosthesis. The harm of the wear depends on the size and the volume of the particles and the overall volume of debris is of importance. The depth and the direction of the polyethylene sinking (i.e. the so-called three-dimensional linear wear) can be accurately assessed from plain radiographs. Some formulas have been proposed to calculate the polyethylene sinking volume (i.e. the so-called wear volume) from the penetration depth of the head as assessed on plain radiographs, based on idealized geometrical models of a prosthetic hip. However, for those published formulas not all of them are correct. Besides, the contributors of the polyethylene sinking include wear and creep, but previous studies were unable to quantify the amount of creep, so they have referred to this combined deformation process as wear. In the first year, this project will derive a reasonable theory for liner sinking. The 3D linear wear methodology and the formula of anteversion of the acetabular cup, which we have published, will be both combined with the derived theory to calculate the sinking volume. Besides, this project will survey the previous formulas and use the retrieved cups to carry out a validation. We estimate that can accomplish a reasonable formula and measuring process for accurately assessing the wear volume of acetabular cups by only one plain radiograph. In the second year, a clinical analysis containing at least 100 metal-backed cementless acetabular cups will be preceded. Effects of the size of the femoral head, the anteversion or inclination of the acetabular cup, or the leg length difference (if exists) on the polyethylene sinking volume will be discussed. In addition, almost 30 retrieved cups are schemed to quantify the amount of creep and wear. Results will be helpful for the selection, match, operation, and the follow up of long term effect of total hip prosthesis.人工髖關節生物性失效是由於植入物附近的骨組織對聚乙烯磨耗碎粒發生溶解反 應，進而導致植入物的鬆脫。這種因磨耗而導致的危害程度，則與微粒的大小、數量、 和總體積有關。 目前已經可以從X 光片來估算髖臼杯凹陷深度和方向(即三維線性磨耗量)。雖然文 獻上也有一些公式用以計算其凹陷之體積(即體積磨耗量)；但是，這些公式卻顯示不盡 然正確。另一方面，雖然髖臼杯內襯的凹陷成因已經知道包含研磨以及潛變兩因素， 但仍未見文獻量化該潛變的體積缺損，只能一直將凹陷之體積視為磨耗碎粒總體積。 本計畫第一年擬先推導出髖臼杯凹陷總體積之分析理論，再結合我們所發表的三 維線性磨耗演算法以及髖臼杯前翻角計算公式，以計算出凹陷區域之體積。此外，將 一併檢視其他文獻所提出的公式，並以從病患身上取下之髖臼杯進行驗證。我們預計 可完成一以一張前後照X 光片即可正確計算聚乙烯凹陷體積之理論公式與測量程序。 在第二年中，本計畫將進行100 例以上無骨泥式髖臼杯之臨床X 光片分析，以瞭 解人工股骨頭大小、髖臼杯傾斜角與前翻角、以及腿長差異(假如存在)等因素對聚乙烯 磨動之影響。同時，將分析30 例以上取出之髖臼杯，藉以量化實際磨耗量以及由潛變 所造成的體積缺損量。Project