2026-11-092026-11-09https://scholars.csmu.edu.tw/handle/123456789/38628Polybrominated diphenyl ethers（PBDEs）have been widely used as brominated flame retardants（BFRs）for varius electronics and electronic manufactures, plastics, textiles and construction material. PBDEs are importment global pollutant for environmental hormone effect and bioaccumulation effect in biota. The structural formulas of PBDEs are like the structural of thyroxine, and PBDEs could disrupt thyroid gland function, neurobehavior effect and carcinogen. Polybrominated diphenyl ethers contaminate biota by food chain and were detected in various environmental matrices, including water, sediment and air and various organisms, including aquatic and terrestrial ecosystems, even human. For the purpose of assessing the Taiwan resident individual exposure source and exposure levels of PBDEs, this study will undergo a series measurement of these substance including food and environmental air. And this study shall provide the valuable information for the integrated project. A two-years projects are proposed here as following. 1. Assessment daily intake of PBDEs through foodstuffs for Taiwanese. 2. Determination PBDEs concentration of indoor and outdoor air of general area and high pollutant places and surroundings, and assessment daily inhalation of PBDEs for residents in Taiwan.多溴二苯醚（polybrominated diphenyl ethers, PBDEs）為最常被使用的溴化阻燃 劑（brominated flame retardants, BFRs），廣泛使用於電器及電子產品、家用產品、塑 膠、紡織品及建材物料等，因其於環境中不易被降解，且具環境荷爾蒙效應，已引 起廣泛注意。PBDEs 之結構式近似動物體上的甲狀腺素，會干擾體內荷爾蒙作用， 對神經行為產生毒性及致癌性。 由於PBDEs 廣泛添加在日常生活產品中，一旦暴露到此類物質，會經由生命週 期及生物傳遞蓄積於食物鏈中，甚至逸散至空氣中，造成河川底泥、空氣及食物等 生活環境的污染，會經由各種途經進入人體，造成公共衛生問題和人體健康之影響。 為評估PBDEs 於國人的暴露情形，第一要務必須了解國人每天可能的攝取量或吸入 量。 為評估國人的暴露情形，本研究配合整合型計畫，針對各種食物（尤其是脂肪含量 較高之食物）進行分析，用以評估經由飲食之PBDEs 攝取量，亦針對一般地區之室 內和室外及高污染場所環境空氣、粉塵中PBDEs 之濃度進行採樣測定，藉此評估國 人主要之暴露來源及暴露量。因此，擬進行二年之研究，第一年：國人經由食物攝 取之多溴二苯醚暴露評估；第二年：一般地區之室內和室外及高污染場所環境空氣 中PBDEs 濃度分析。多溴二苯醚每日攝取量環境暴露polybrominated diphenyl ethersdaily intakeenvironmental exposureProject