2026-08-252026-08-25https://scholars.csmu.edu.tw/handle/123456789/16880Pemetrexed is a novel multitargeted antifolate that inhibits one or several key folate-requiring enzymes of the thymidine and purine biosynthetic pathways, in particular, thymidylate synthase (TS)...(詳)Pemetrexed (愛寧達，Alimta)為葉酸拮抗劑抗癌藥物，作用機轉是分別抑制 glycinamide ribonucleotide formyltransferase (GARFT)...(詳)肺腺癌抗葉酸類抗癌藥愛寧達抗藥性lung adenocarcinomaantifolatedrug resistancepemetrexedresearch project