CHENG-MING PENG2026-10-162026-10-162008-09-01Pure ID: 15418931Pure UUID: eb81eff6-1c1f-425c-b82a-07d2db0483cchttps://www.scopus.com/pages/publications/56049127953https://scholars.csmu.edu.tw/handle/123456789/33111Juvenile polyposis syndrome is a rare hamartomatous disorder. It is categorized into three subgroups based on clinical presentation: generalized juvenile polyposis, juvenile polyposis coli, and juvenile polyposis of infancy. The symptoms and signs include acute or chronic gastrointestinal bleeding, anemia, prolapsed rectal polyps, abdominal pain and diarrhea. Juvenile polyposis syndrome is associated with an increased risk of gastrointestinal malignancy. We report a 49-year-old woman with a multi-year history of severe anemia. Endoscopy disclosed multiple polyps in the gastric antrum and body. Histologic examination of the biopsy specimens revealed generalized juvenile polyposis. The patient underwent total gastrectomy and Roux-en-Y esophagojejunostomy. There was no evidence of disease recurrence at two-year follow-up.5enjournal article