CHUAN-MIAO LIAO2026-10-162026-10-162005-08-31Pure ID: 15199283Pure UUID: 655414a7-4e57-4979-b258-d4e2748813bf10.1016/j.autneu.2005.05.007https://www.scopus.com/pages/publications/24344503700https://scholars.csmu.edu.tw/handle/123456789/33958The static/dynamic changes of gas exchange, heart rate (HR) and blood pressure in terms of work rate (WR) and WR changes in ramp exercise were investigated by cardio-pulmonary exercise tests (CPETs) in hyperhidrosis patients before (W0), one week (W1) and four weeks (W4) after bilateral T2-sympathectomy. Accompanied by constant oxygen consumption and WR at peak exercise and similar oxygen debt in recovery, the HR significantly (p < 0.05) decreased statically in all stages of CPET, but was not altered dynamically, i.e., similar slope but significantly diminished intercept in HR changes versus WR changes (70 ± 6.0 vs. 82 ± 19 beats/min, p < 0.01), in W1 (n = 11), compared to W0 (n = 13). However, this surgical effect on static HR changes seemed to have disappeared in W4 (n = 8), albeit at that time the static blood pressure decreased significantly during exercise. These findings suggest that bilateral T2-sympathectomy will reduce static HR without causing cardiovascular insufficiency in one week, and would then recover by one month in hyperhidrosis patients.7enjournal article