2026-09-292026-09-29https://scholars.csmu.edu.tw/handle/123456789/19431In this project, we aim to develop the hybrid delivery systems with hypoxia-targeting and detection ability. We focus on the human NQO1 reductase, which is usually over-expressed in solid tumors u...(詳)本年度計畫主要嘗試開發具有標靶缺氧特質的複合藥物傳遞與診斷系統。我們鎖定超過50%的癌細胞皆有過度表現的人類NQO1還原性酵素,開發出樹枝狀高分子衍生之螢光探針來分析此酵素在不同腫瘤細胞的表現...(詳)香豆素樹枝狀高分子偶氮苯藥物釋放缺氧偵測還原性酵素癌症治療Coumarinsdendrimersazobenzenesdrug releasehypoxia detectionreductasecancer therapy具有缺氧標靶特性的光控藥物傳遞系統的開發與其在癌球幹細胞的偵測與治療上的應用Project