KAN-JEN TSAI2026-10-162026-10-161996-08-02Pure ID: 14992270Pure UUID: b6a0a780-36f3-4947-b3e0-6b9fe175f52610.1016/0024-3205(96)00377-3https://www.scopus.com/pages/publications/0030564889https://scholars.csmu.edu.tw/handle/123456789/34052Glucose-6-phosphate dehydrogenase (G6PD) deficient red blood cells (RBCs) are known to be more susceptible to oxidant-induced hemolysis. Erythrocytes from G6PD-deficient individuals are significantly more susceptible to Ca2+-induced vesiculation than normal control cells. The enhanced susceptibility of G6PD-deficient RBCs to Ca2+-induced vesiculation is not due to ATP depletion. The remnant G6PD-deficient RBCs following vesiculation are more sensitive to complement-mediated hemolysis than control normal RBCs. A strong positive correlation exists between the level of Ca2+-induced vesiculation and the extent of complement mediated hemolysis.10enjournal article