SHINN-JYH DING2026-10-162026-10-162007-07-15Pure ID: 15115021Pure UUID: 7446d1c0-2797-460c-b4be-16c48c9c711410.1016/j.jnoncrysol.2007.04.020https://www.scopus.com/pages/publications/34249941063https://scholars.csmu.edu.tw/handle/123456789/27482A variety of biomimetic materials with structural and mechanical equivalence to bone have been developed to repair bone defects. Chitosan/calcium phosphate composites composed of bioactive calcium phosphate and flexible chitosan were made by a simple mixing-and-heating method. Mechanical properties, morphology, phase composition, and weight change after immersion in Hanks' solution were evaluated. Experimental results showed that the formation of pores/cracks on immersed sample surface obviously depended on the calcium phosphate content and immersion time. The immersion time imposed in this study did have a statistically significant effect on mechanical properties. When immersed for 90 days in Hanks' solution, the strength of immersed composites containing 10 wt/v% calcium phosphate with the initial strength of 27 MPa was about 2 MPa, having a reduction of 92%. Based on the above results, the organic-inorganic hybrid composites with high initial strength might be an acceptable material candidate for bone tissue repair.7enjournal article