2026-08-252026-08-25https://scholars.csmu.edu.tw/handle/123456789/17044Calorie restriction (CR) extends lifespan and decreases the occurrence of age-related diseases through the increase in intracellular NAD+ levels followed by activation of SIRT1 protein. A calorie ...(詳)熱量限制可以藉由增加細胞內NAD+濃度，進而活化SIRT1而能延長壽命和降低老化相關疾病的發生率。熱量限制模仿劑(CRM)指化學分子或天然分子具有和熱量限制相同的作用，但不需要透過飲食限制的方...(詳)熱量限制模仿劑維生素B3菸鹼醯氨六菸鹼酸肌醇NAD+SIRT1calorie restriction mimeticvitamin B3nicotinamideinositol hexanicotinateNAD+SIRT1research project