陳志毅Chih-Yi Chen陳柏谷Po-Ku Chen醫學研究所碩士班2026-10-292026-07-1620262026-06-25https://handle.ncl.edu.tw/11296/buu6kzhttps://scholars.csmu.edu.tw/handle/123456789/36771研究目的：臨床上，中醫常透過針灸與中藥等方法，改善癌症患者因常規西醫治療所引發的副作用 。本研究旨在評估中醫輔助治療對乳癌患者生活品質之改善成效，並進一步探討不同癌症期別與西醫治療方式，是否會影響中醫介入的療效表現 。研究方法及資料：本研究採回溯性世代研究設計，擷取2018至2022年間中山醫學大學附設醫院資料庫之病歷資料 。篩選條件為年齡20至80歲、在接受標準西醫治療後合併中醫照護的乳癌患者 。納入對象須完成至少兩次（含）以上之「癌症治療功能性評估一般量表」（FACT-G）評估 。研究結果：本研究自2018至2022年間共篩得193名同時接受西醫與中醫照護之乳癌患者，經排除不符合條件或未完成至少兩次FACT-G評估者後，最終納入68名患者進行分析，其中60名完成三次評估。統計分析顯示，中醫介入治療兩個月後，患者的「生理健全狀況」（PWB, p=0.005）與「情緒健全狀況」（EWB, p=0.017）獲得顯著改善 。介入四個月後，除了PWB（p=0.020）與EWB（p=0.002）持續進步外，整體的「生活品質總分」（FACT-G Total Score, p=0.026）亦達到統計學上之顯著提升 。進階分析發現，癌症期別以及是否接受放射治療、化學治療、抗荷爾蒙治療或標靶治療，皆不影響中醫改善生活品質的成效 。然而，「是否接受外科手術」則具有顯著影響力；相較於未接受手術者，有手術的患者在中醫介入後，其情緒狀況及整體生活品質均呈現更顯著的改善（p<0.05）。結論與建議：中醫輔助治療能顯著提升乳癌患者的生理及情緒生活品質 。此療效具備高度普適性，不受癌症期別與各類西醫藥物治療的影響，且對於術後患者的身心重建尤具效益 。建議未來研究納入未接受中醫治療之患者作為對照組，並執行前瞻性試驗，以更全面地評估中醫介入的真實臨床價值 。Objective: Traditional Chinese Medicine (TCM) utilizes modalities such as acupuncture and herbal medicine to alleviate the side effects of conventional cancer treatments. This study aims to evaluate the efficacy of TCM as an adjunctive therapy in improving the quality of life (QoL) of breast cancer patients, and to investigate whether different cancer stages or Western medical treatment modalities influence the degree of this improvement.Methods and Materials: A retrospective cohort study was conducted using the database of Chung Shan Medical University Hospital from 2018 to 2022. The study included breast cancer patients aged 20 to 80 who received conventional Western medical treatments followed by TCM intervention. To be included, patients were required to have completed the Functional Assessment of Cancer Therapy-General (FACT-G) scale at least twice.Results: A total of 193 breast cancer patients were initially identified. After excluding patients who did not meet the eligibility criteria or did not complete at least two FACT-G assessments, 68 patients were included in the final analysis, of whom 60 completed three assessments. After two months of TCM intervention, patients demonstrated significant improvements in physical well-being (PWB, p=0.005) and emotional well-being (EWB, p=0.017). After four months of intervention, in addition to the continuous improvements in PWB (p=0.020) and EWB (p=0.002), there was also a significant increase in the overall QoL score (p=0.026). Subgroup analyses indicated that the degree of QoL improvement by TCM was not significantly affected by cancer stage or the administration of radiotherapy, chemotherapy, hormone therapy, or targeted therapy. However, surgical treatment significantly influenced the outcomes; compared to non-surgical patients, those who underwent surgery experienced a significantly greater improvement in emotional well-being and overall QoL (p<0.05).Conclusion and Suggestions: TCM adjunctive treatment significantly improves the physical and emotional quality of life in breast cancer patients. This beneficial effect is universally applicable regardless of disease stage or specific Western pharmacological treatments, with surgical patients showing particularly pronounced emotional benefits. Future prospective studies incorporating non-TCM control groups are recommended to provide a more comprehensive evaluation of its clinical efficacy.乳癌中醫生活品質癌症治療功能性評估一般量表 (FACT-G)Breast CancerTraditional Chinese MedicineQuality of LifeFACT-Gthesis