CHIN-LIN HSU2026-10-162026-10-162025-01-01Pure ID: 15393997Pure UUID: 2ef0ec47-d34b-4cf5-aa0d-7817ea518b6e10.38212/2224-6614.3527https://www.scopus.com/pages/publications/105001876622https://scholars.csmu.edu.tw/handle/123456789/27099This study investigated the preventive effects of a 40% ethanol extract of Hsian-tsao (40EEHT) on obesity in high-fat diet (HFD)-induced obese rats. Male Wistar rats were administered 0, 100, 200, or 500 mg/kg of 40EEHT, resulting in reduced body weight, total body fat, and hepatic tissue weight after 8 weeks. 40EEHT also decreased adipocyte size, improved lipid profiles, alleviated oxidative stress, and enhanced hepatic antioxidant enzyme activities. Additionally, it regulated fatty acid metabolism by reducing lipogenesis and increasing lipolysis and b-oxidation, suggesting its potential as an anti-obesity dietary supplement.13enjournal article